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Ferenc G Rick Selected Research

cetrorelix (Cetrotide)

6/2013Mechanisms of synergism between antagonists of growth hormone-releasing hormone and antagonists of luteinizing hormone-releasing hormone in shrinking experimental benign prostatic hyperplasia.
4/2013Re: editorial comment on LHRH antagonist cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia (Prostate 2011; 71: 736-747).
4/2012Combining growth hormone-releasing hormone antagonist with luteinizing hormone-releasing hormone antagonist greatly augments benign prostatic hyperplasia shrinkage.
4/2012Inhibitory effects of antagonists of growth hormone releasing hormone on experimental prostate cancers are associated with upregulation of wild-type p53 and decrease in p21 and mutant p53 proteins.
5/2011LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia.
10/2009Triple-negative breast cancers express receptors for luteinizing hormone-releasing hormone (LHRH) and respond to LHRH antagonist cetrorelix with growth inhibition.

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Ferenc G Rick Research Topics

Disease

34Neoplasms (Cancer)
01/2018 - 09/2006
17Prostatic Neoplasms (Prostate Cancer)
06/2017 - 12/2008
7Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2018 - 03/2011
7Triple Negative Breast Neoplasms
01/2016 - 10/2009
3Inflammation (Inflammations)
01/2018 - 01/2014
3Urinary Bladder Neoplasms (Bladder Cancer)
01/2016 - 07/2012
3Myocardial Infarction
01/2015 - 01/2012
3Colorectal Neoplasms (Colorectal Cancer)
01/2015 - 08/2010
3Glioblastoma (Glioblastoma Multiforme)
01/2014 - 03/2013
3Neoplasm Metastasis (Metastasis)
12/2013 - 10/2010
3Colonic Neoplasms (Colon Cancer)
11/2012 - 10/2009
2Lymphoma (Lymphomas)
01/2017 - 01/2015
2Adenocarcinoma
01/2017 - 06/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2015 - 09/2006
2Breast Neoplasms (Breast Cancer)
01/2015 - 09/2012
2Melanoma (Melanoma, Malignant)
01/2015 - 01/2014
2Edema (Dropsy)
07/2013 - 02/2012
2Carcinoma (Carcinomatosis)
08/2010 - 09/2006
1Prostatitis
01/2018
1Renal Cell Carcinoma (Grawitz Tumor)
01/2017
1Dyslipidemias (Dyslipidemia)
02/2016
1Hyperglycemia
02/2016
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
02/2016
1Chronic Renal Insufficiency
02/2016
1Papillary Thyroid Cancer
06/2015
1Heart Failure
01/2015
1Pneumonia (Pneumonitis)
07/2013
1Autolysis
07/2013

Drug/Important Bio-Agent (IBA)

22Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA
01/2018 - 09/2006
16Gonadotropin-Releasing Hormone (GnRH)FDA Link
06/2017 - 10/2009
11Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018 - 12/2008
10AndrogensIBA
01/2017 - 12/2008
9somatotropin releasing hormone receptorIBA
01/2017 - 10/2010
8Doxorubicin (Adriamycin)FDA LinkGeneric
01/2015 - 09/2009
6Har(29)- Arg(28) Nle(27) Orn(21) His(20) Orn(12,) Abu(15) His(11) Tyr(Me)(10) Har(9) Ala(8) Fpa(5,6) Arg(2) (PhAc-Ada)(0)-Tyr(1) GHRH(1-29)NH2IBA
01/2017 - 09/2012
6Hormones (Hormone)IBA
01/2017 - 09/2012
6cetrorelix (Cetrotide)FDA Link
06/2013 - 10/2009
5CytokinesIBA
01/2018 - 05/2011
5lysine(6)-doxorubicin LHRHIBA
01/2016 - 07/2012
5PhAcTyr(1)- Arg(2)- P(H)e(4- CL)(6)- Ala(8)- Tyr(Me)(10)- His(11)- Abu(15)- His(20)- Nle(27)- Arg(28)- HLCr(29)- GHRH(1-29)NH2IBA
06/2013 - 10/2009
4Peptides (Polypeptides)IBA
01/2016 - 03/2011
4LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
01/2016 - 07/2012
4Cytotoxins (Cytolysins)IBA
01/2016 - 07/2012
4Gastrin-Releasing PeptideIBA
05/2014 - 07/2012
3Messenger RNA (mRNA)IBA
01/2017 - 09/2009
3NeuropeptidesIBA
01/2017 - 04/2012
3Phosphotransferases (Kinase)IBA
06/2015 - 01/2012
3Irinotecan (Camptosar)FDA LinkGeneric
01/2015 - 07/2012
3Fluorouracil (Carac)FDA LinkGeneric
01/2015 - 07/2012
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2014 - 12/2008
3BombesinIBA
05/2014 - 07/2012
3Testosterone (Sustanon)FDA Link
06/2013 - 04/2012
3Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
02/2013 - 09/2009
3Proteins (Proteins, Gene)FDA Link
10/2012 - 12/2008
3MZ-J-7-138IBA
04/2012 - 09/2006
2Peptide Receptors (Peptide Receptor)IBA
06/2017 - 05/2014
2Growth Hormone (Somatotropin)IBA
02/2016 - 09/2012
2Docetaxel (Taxotere)FDA Link
01/2015 - 09/2006
2Cisplatin (Platino)FDA LinkGeneric
01/2015 - 11/2012
2MIA-690IBA
01/2014 - 01/2014
2Streptococcus pneumoniae plY proteinIBA
07/2013 - 02/2012
2Somatostatin Receptors (Somatostatin Receptor)IBA
02/2013 - 09/2009
2Hca(6)-Leu(13)-psi(CH2N)-Tac(14)- bombesin(6-14)IBA
10/2012 - 07/2012
2RC 121IBA
08/2010 - 09/2009
1CarrageenanIBA
01/2018
1Human Growth Hormone (Saizen)FDA LinkGeneric
01/2017
1Cadherins (E-Cadherin)IBA
01/2017
1Conditioned Culture MediaIBA
01/2017
1Follicle Stimulating Hormone (Follitropin)FDA Link
01/2017
1Triglycerides (Triacylglycerol)IBA
02/2016
1Lipoproteins (Lipoprotein)IBA
02/2016
1AN 207IBA
01/2016
1Finasteride (Propecia)FDA LinkGeneric
01/2016
1Hypothalamic HormonesIBA
11/2015
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
06/2015
1Matrix Metalloproteinases (MMPs)IBA
06/2015
1AMP-Activated Protein KinasesIBA
05/2015
1Calcium-Calmodulin-Dependent Protein Kinase KinaseIBA
05/2015
1ErbB Receptors (EGF Receptor)IBA
05/2014
1JI-38IBA
02/2014
1N-Me-Tyr1,D-Ala2,Asn8,Arg29-NHCH3-JI-38IBA
02/2014
1MR 356IBA
02/2014
1Pharmaceutical PreparationsIBA
01/2014
1Dihydrotachysterol (AT 10)IBA
01/2014
1cadherin 5IBA
01/2014
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
12/2013
1Tumor Biomarkers (Tumor Markers)IBA
12/2013
1CD146 AntigenIBA
12/2013
1Metalloproteases (Metalloproteinases)IBA
12/2013
1S100 Calcium-Binding Protein A4IBA
12/2013
1Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)IBA
12/2013
1SynucleinsIBA
12/2013
1Anti-Bacterial Agents (Antibiotics)IBA
07/2013
1CholesterolIBA
07/2013
1SodiumIBA
07/2013
1Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA
07/2013
1Adenosine Triphosphatases (ATPase)IBA
07/2013

Therapy/Procedure

17Therapeutics
06/2017 - 12/2008
5Castration
01/2016 - 01/2012
2Drug Therapy (Chemotherapy)
01/2015 - 01/2014